Quique Bassat

Institut de Salut Global Barcelona

Life & Medical Sciences

Quique Bassat is an ICREA Research Professor at the Barcelona Institute of Global Health (ISGlobal). He has a degree in Medicine from the Universitat de Barcelona (UB, 1999), a specialization in pediatrics (UaB, 2004), and Masters in Tropical Medicine and International Health (UB, 2004) and Epidemiology (LSHTM, 2008). He obtained his PHD in the year 2009 (UB) with work on the treatment and clinical characterization of malaria in Africa. He has been based for several years at the Centro de Investigação em Saúde de Manhiça (CISM), in Mozambique, where he currently conducts most of his research, although in recent years he has started projects in other countries, including Morocco, Papua New Guinea, Brazil or Bhutan. 

Research interests

As a paediatrician, my research is based on the premise that there is no greater public health intervention than that which can reduce child mortality, particularly in poor contexts. To do these, I have worked in low and middle-income countries to understand and prevent malaria, yaws and other infectious diseases that most impact child survival. I have investigated in Mozambique, Morocco, Papua New Guinea, Brazil and now Bhutan, the epidemiology, aetiology and clinical characteristics of malaria, pneumonia, diarrhea, neonatal sepsis, Yaws and other infectious diseases significantly affecting child's health. I’m interested in biomarkers of host response as diagnostic and prognostic tools to help triage children and better target antibiotics. For malaria and yaws, my research is contributing to develop and test the new paradigm of disease eradication, by assessing the impact of drugs to specifically interrupt their transmission. More recently, my research has focused on improving the poor existing data on the causes of child mortality. An important contribution has been the validation of a radically innovative minimally invasive autopsy (MIA) sampling protocol.

Selected publications

- Gargano N, Madrid L, Valentini G, D'Alessandro U, Halidou T, Sirima S, Tshefu A, Mtoro A, Gesase S, Bassat Q 2018, 'Efficacy and Tolerability Outcomes of a Phase II, Randomized, Open-Label, Multicenter Study of a New Water-Dispersible Pediatric Formulation of Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in African Infants', Antimicrobial Agents And Chemotherapy, 62, 1, e00596-17.

- Madrid L, Amos Maculuve S, Vilajeliu A, Saez E, Massora S, Cossa A, Varo R, Sitoe A, Mosqueda N, Anselmo R, Munguambe K, Soto SM, Moraleda C, Macete E, Menendez C & Bassat Q 2018, 'Maternal Carriage of Group B Streptococcus and Escherichia coli in a District Hospital in Mozambique', Pediatric Infectious Disease Journal, 37, 11, 1145 - 1153.

- Galatas B, Marti-Soler H, Nhamussua L, Cistero P, Aide P, Saute F, Menendez C, Rabinovich NR, Alonso PL, Bassat Q & Mayor A 2018, 'Dynamics of Afebrile Plasmodium falciparum Infections in Mozambican Men', Clinical Infectious Diseases, 67, 7, 1045 - 1052.

- Mitja O, Godornes C, Houinei W, Kapa A, Paru  R, Abel H, Gonzalez-Beiras C, Bieb SV, Wangi J, Barry AE, Sanz S, Bassat Q, Lukehart SA & Sheila A 2018, 'Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study', Lancet, 391, 10130, 1599 - 1607.

- Moraleda C, Benmessaoud R, Esteban J, Lopez Y, Alami H, Barkat A, Houssain T, Kabiri M, Bezad R, Chaacho S, Madrid L, Vila J, Munoz-Almagro C, Bosch J, Soto SM & Bassat Q 2018, 'Prevalence, antimicrobial resistance and serotype distribution of group B streptococcus isolated among pregnant women and newborns in Rabat, Morocco', Journal Of Medical Microbiology, 67, 5, 652 - 661.