Ciara O' Sullivan received a BSc in Analytical Chemistry from Dublin City University in 1992, a PhD in Biotechnology from Cranfield University in 1996 and then went on to lead the sensors group at University College Cork from 1996-99. She then took up a Marie Curie Fellowship at the Universitat Rovira i Virgili (1999-2001) and was then awarded a Ramón y Cajal Fellowship which she pursued for 1 year prior to taking up her current position as ICREA Research Professor and establishing the Nanobiotechnology and Bioanalysis Group at the Universitat Rovira i Virgili. She is group leader of the GENCAT funded Consolidated Group INTERFIBIO. Her group details can be found at www.interfibio.com.
Research interests
Her research interests lie in the development of electrochemical and optical biosensors exploiting advances in tailored biocomponents. Presently, her work focuses on reducing to practise cost-effective molecular diagnostics for screening and monitoring of disease, as well as on the development of aptamers for application in optical and electrochemical molecular aptamer beacons. The approaches for molecular diagnostics being developed include parallelised real-time electrochemical next generation sequencing, electrochemical array based primer extension and elongation for multiplexed SNP detection, multiplexed electrochemical miRNA detection and quantitative paper diagnostics as companion tools for the future paradigm of pharmacogenomics and personalised medicine.
Selected publications
- Pedreira-Rincón J, Rivas L, Comenge J, Skouridou V, Camprubi-Ferrer D, Muñoz J, O'Sullivan CK, Chamorro-Garcia A & Parolo C 2025, 'A comprehensive review of competitive lateral flow assays over the past decade', Lab on a chip, 25 - 11 - 2578 - 2608.
- Mairal-Lerga T, Redondo MCB, Skouridou V, Jauset-Rubio M & O'Sullivan CK 2025, 'Aptamer lateral flow assay for the rapid detection of histamine in fish and human blood', Journal of hazardous materials, 494 - 138540.
- Justo CAC, Acosta SJ, Jauset-Rubio M, Skouridou V, Mulinganya G, Cools P, Rivera WL & O'Sullivan CK 2025, 'Isothermal DNA Amplification with Tailed Primers Coupled with Enzyme-Linked Oligonucleotide Assay for the Sensitive Detection of Trichomonas vaginalis', Acs infectious diseases, 11 - 7 - 1944 - 1955.
- Ondrus M, Franco-Urquijo PA, Lerga TM, Cechová LM, Redondo MCB, O'Sullivan CK & Hocek M 2025, 'Versatile Enzymatic Approach for Truncation, Labeling, and Mutation of Nucleobase-Modified Aptamers Demonstrated on Indole-Modified β-Conglutin Aptamer', Chembiochem, 26 - 20.
- DeCruz AT, Miller BS, Huang D, McRobbie M, Donaldson F, McCoy LE, O'Sullivan CK, Botha JC, Nastouli E & McKendry RA 2025, 'Quantum-enhanced nanodiamond rapid test advances early SARS-CoV-2 antigen detection in clinical diagnostics', Nature communications, 16 - 1 - 8778.
Selected research activities
Associate Editor, Analytical Chemistry (ACS)
Associate Editor, ACS Measurement Science Au (ACS)
Industrial Contract from Muun Health (Estonia) for the selection of aptamers against progesterone
PI of SGR Consolidated Research Group, INTERFIBIO