Iñaki Ruiz-Trillo

Institut de Biologia Evolutiva

Life & Medical Sciences

Iñaki Ruiz-Trillo is an ICREA Research Professor at the Institut de Biologia Evolutiva (CSIC-UPF) in Barcelona. His educational background includes a B.S. and a PhD in Biology from the University of Barcelona. Funded by grants from EMBO and the Canadian Institutes of Health Research, he completed a post-doctoral fellowship at Dalhousie University (Canada). He has also performed short term research projects at the Joint Genome Institute, the University of Arkansas and the Kavli Institute for Theoretical Physics. Iñaki has published more than 60 peer-reviewed articles, most of them in high impact journals, such as Cell, Science, eLife, and PNAS. He has lead several research projects, including 2 ERC grants. He is an EMBO member, F1000 Faculty member and serves in the editorial board of several journals. His current research interests include the origin of multicellular animals and the evolution of complex life forms.


Research interests

The lab is interested in understanding how multicellular animals emerged from their unicellular ancestors. To this aim we perform comparative genomic analyses between multicellular animals and their closest unicellular relatives to unravel the nature of the unicellular ancestor that gave rise to animals. We are also currently developing molecular techniques and transgenesis tools in the closest unicellular relatives to Metazoa. Finally, we are also interested in unravelling the hidden diversity among opisthokonts lineages using metabarcoding data.  

Selected publications

- Sebé-Pedrós A & Ruiz-Trillo I 2017, 'Evolution and Classification of the T-Box Transcription Factor Family', Current Topics in Developmental Biology, 122:1-26

- Sebe-Pedros A, Degnan BM & Ruiz-Trillo I 2017, 'The origin of Metazoa: a unicellular perspective', Nature Reviews Genetics, 18, 8, 498 - 512.

- Grau-Bove X, Torruella G, Donachie S, Suga H, Leonard G, Richards TA & Ruiz-Trillo I 2017, 'Dynamics of genomic innovation in the unicellular ancestry of animals', Elife, 6, e26036.

- Ferrer-Bonet M & Ruiz-Trillo I 2017, 'Capsaspora owczarzaki', Current Biology, Vol 27, Issue 17. 

- López-Escardó D, Grau-Bové X, Gillaumet-Adkins A, Gut M, Sieracki ME & Ruiz-Trillo I 2017, 'Evaluation of single-cell genomics to address evolutionary questions using three SAGs of the choanoflagellate Monosiga brevicollis', Scientific Reports 7.11025.


Selected research activities

Appointed vice-director of the Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra).

Elected EMBO member.