George Altankov

Institut de Bioenginyeria de Catalunya (IBEC)

Experimental Sciences & Mathematics

I graduated from the Higher Medical Institute, Varna, Bulgaria, in 1974 where I also started my research carrier as Assistant Perofessor in the Dept. of Physiology. After obtaining my PhD in 1984 I joined the Bulgarian Academy of Sciences (Institute of Biophysics Sofia) where I got my first habilitation as Associate Professor (1994) and grew up to Full Professor (2002), head of Department "Cell Adhesion" and Research Director. I would describe myself as an interdisciplinary-oriented scientist working in the field of cell-biomaterial interaction and tissue engineering. In 1991-1993 I was postdoc in Southwestern Medical Center Dallas and during the following decade I spent more than 7 years as guest-scientist in Germany and France, and later almost 2 years in Spain. Since April 2007 I am ICREA Research Professor at the Institute for Bioengineering of Catalonia (IBEC) heading the new research group Molecular Dynamics at Cell-Biomaterials Interface.

Research interests

I am working in the field of cell-biomaterials interaction and tissue engineering. On that topic I have published more than 90 original papers and filed 5 patents. As ICREA Research Professor at Institute for Bioengineering of Catalonia (IBEC) I have created a new research group Molecular dynamics at cell-biomaterials interface, where we seek to understand the cellular mechanisms that determine biocompatibility of materials. My research interests might be summarized as follows: -Cell-biomaterials interaction -Development of provisional extracellular matrix at biomaterials interface -Nanofibers design and production via electrospinning -Tissue engineering -Controlled differentiation of mesenchimal stem cells -In situ endothelization and neovascularization of implants.

Selected publications

– Zhao M, Altankov G, Grabiec U, Bennett M, Salmeron-Sanchez M, Dehghani F & Groth T 2016, ‘Molecular composition of GAG-collagen I multilayers affects remodeling of terminal layers and osteogenic differentiation of adipose-derived stemcells’, Acta Biomaterialia, 41, 86 – 99.

– Coelho N M, Llopis-Hernández V, Salmerón-Sánchez  & Altankov G 2016, ‘Dynamic Reorganization and Enzymatic Remodeling of Type IV Collagen at Cell–Biomaterial Interface’, In Christo Z. Christov, editor: Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods,Vol 105, APCSB, UK: Academic Press, pp. 81-104.

– Forget J, Awaja F, Gugutkov D, Gustavsson J, Gallego Ferrer G, Coelho-Sampaio T, Hochman-Mendez C, Salmeron-Sánchez M & Altankov G 2016, ‘Differentiation of Human Mesenchymal Stem Cells Toward Quality Cartilage Using Fibrinogen-Based Nanofibers’, Macromol. Biosci. 16, 9, 1348 – 1359.

Selected research activities

Keynote -Nanomedicine 2016- Nanomedicine and Nanotechnology in Health Care, July 25-27 Bangkok, Thailand, Title: “Mesenchymal “Stem Cells Behaviour in Nanofibrous Environment”

Coordinator European Project: FP7-PEOPLE-2012-IAPP (2013-2016) –FIBROGELNET– “Network for Development of Soft Nanofibrous Construct for Cellular Therapy of Degenerative Skeletal Disorders”

PI National Project: MAT 2015 – 69315 –C3 (2015-2017) – MYOHEAL – Muscle regeneration after injury. Engineered biodegradable ion–loaded scaffolds to promote muscle regeneration. Collaborative Project funded by Spanish Ministry of Science and Innovation

Associate Editor Journal of Biomaterials and Tissue Engineering