Pablo Menéndez

Institut de Recerca contra la Leucèmia Josep Carreras (IJC)

Life & Medical Sciences

Born in Avilés, Asturias, in 1974. Biochemist by University of Salamanca (1997) and PhD in Medicine (Hematology) by the same University in 2002, under the supervision of Prof. Alberto Orfao and Prof. Jesús San Miguel. Postdoctoral training in stem cell biology (Mick Bhatia Laboratory, London, ON, Canada; 2002-2005) and in childhood leukemia (Mel Greaves Laboratory, London, UK; 2005-2007). In 2007, I was appointed Director of the Andalusian Stem Cell Bank, and was leading my own lab at CIBM (Granada, Spain) until July 2011 when I moved to GENyO (Granada, Spain) as Principal Investigator. In June 2013 I was appointed ICREA Research Professor and Research Director of The Josep Carreras Leukemia Research Institute-Campus Clínic, Barcelona, Spain.

Research interests

1.- Modeling Infant Acute Lymphoblastic Leukemia MLL-AF4+.
2.- Sarcomagenesis models based on mesenchymal stem cells.
3.- Leukemic cell-niche environment interactions.
4.- Deciphering the intrinsic determinants and signaling pathways underlying hematopoietic-mesenchymal specification from human PSCs.
5.- Adoptive T-cell-based CAR immunotherapy for B-cell ALL and AML.

Selected publications

– Bueno C, …Menendez P. Leukemia.2016,30:674-82

– Romero-Moya D,……P Menendez*Stem Cell Res 2016 (in press).

– Lavoie J…Menendez P,….Rosu-Myles M. Exp Hematol; 2016: 44,S86 – S87.

– Bueno C et al. Leukemia 2016; 30:1603-1606.

– B Lopez-Millán……..,. P Menendez Exp Mol Med 2016 (in press).

– Muñoz-López A et al. Stem Cells 2016;34:581-587.

– Engert A et al. Haematologica 2016;101:115-208. 

– Hernandez A et al. Int J Mol Sci. 2016;17:461-478.

– Gonzalo-Gil E et al. Arthritis Res Ther. 2016;18:77-85.

– Castaño J et al. Oncotarget 2016;21:30440-30452.

– Prieto C et al. Cancer Res 2016; 76: 2478-2489.

– Sanjuan-Pla, A,….Menendez P.Stem Cells Dev; 2016:25:259-265.

– A. Muñoz-Lopez,……. P. Menendez*. Stem Cell Rep 2016;7:602-18.

– A. Giorgetti,….P Menendez*. Exp Hematol; 2016;45:85-93. 

Selected research activities

Ad Hoc Advisor for the European Food and Safety Authority (EFSA) on Properties of PPP’s linked to childhood leukemia.