Kilian Muñiz

Institut Català d'Investigació Química (ICIQ)

Experimental Sciences & Mathematics

Kilian Muñiz is an ICREA Research Professor at the Institute of Chemical Research of Catalonia (ICIQ), in Tarragona. He was born in 1970 in Hildesheim, Germany. From 1990 to 1996 he studied Chemistry at the Universities of Hannover (Germany), Oviedo (Spain) and Imperial College London (UK), and in 1996 he graduated with a Diploma in Chemistry from Hannover University. From 1996 to 1998 he worked in the group of Prof. Carsten Bolm at the RWTH Aachen (Germany) to obtain his PhD in Organic Chemistry. In 1999/2000 he carried out research as a postdoctoral associate with Prof. Ryoji Noyori at Nagoya University (Japan). He started his independent research in 2001 at Bonn University (Germany) as a Liebig fellow and defended his Habilitation Thesis in 2005. The same year he moved to the University of Strasbourg as an Associate Professor. He was promoted to Full Professor in 2006. In November 2009 he moved to Spain and joined ICIQ as Group Leader. He has been with ICREA since 2010.

Research interests

Our research deals with the discovery of novel chemical transformations to provide direct access to nitrogen containing molecules, which are key players in a variety of compounds of biological, medicinal and pharmaceutical interest. Recently, the group has started to devise entirely new oxidative amination reactions based on transformations that do not require any metal promoters. To this end, defined monomeric hypervalent iodine reagents in the unusual iodine oxidation state of +III incorporating unprecedented iodine-nitrogen bonds were developed. These serve as versatile tools in a variety of novel amination reactions comprising all common hydrocarbon entities. An enantioselective version has already found application in the synthesis of relevant pharmaceuticals. This chemistry is continuously expanded to other iodine catalyses in order to generate effective conceptual tools for advanced oxidation at different stages of chemical synthesis.

Selected publications

– Haubenreisser S, Wöste TH, Martinez C, Ishihara K & Muñiz K 2016, ‘Structurally Defined Molecular Hypervalent Iodine Catalysts for Intermolecular EnantioselectiveReactions’, Angew. Chem. Int. Ed., 55, 413 – 417. Highlighted on the journal cover.

– Lucchetti N, Scalone M, Fantasia S & Muñiz K 2016, ‘Sterically Congested 2,6-Disubstituted Anilines from Direct C-N Bond Formation at an Iodine(III) Center’, Angew. Chem. Int. Ed., 55, 13335 – 13339.

– Martinez C, Bosnidou AE, Allmendinger S & Muñiz K 2016, ‘Towards Uniform Iodine Catalysis: Intramolecular C-H Amination of Arenes under Visible Light’, Chem. Eur. J., 22, 9929 – 9932.

– Fra L & Muñiz K 2016 ‘Indole Synthesis through Sequential Electrophilic N-H and C-H Bond Activation using Iodine(III) Reactivity’, Chem. Eur. J., 22, 4351, Hot Paper (selected by the Editorial Office), Highlighted on the journal backside cover.

– Lucchetti N, Scalone M, Fantasia S & Muñiz K 2016, ‘An Improved Catalyst for Iodine(I/III)-Catalysed Intermolecular CH Amination’, Adv. Synth. Catal., 358, 2093 – 2099. VIP Paper (selected by the Editorial Office), highlighted on the journal cover.

– Martínez C & Muñiz K 2016 ‘Defined Palladium Phthalimidato Catalysts for Improved Oxidative Amination’, Chem. Eur. J., 22, 7367-70.

Selected research activities

– 2016 Yoshida Lectureship from the IOCF Kyoto, Japan.

– Organizer of the 2016 Barluenga Lectureship.

– Planary, Keynote and Invited Lectures at international conferences and research institutions.

– Advisory Board member of the Journal of Organic Chemistry and The Chemical Record.

– Teacher in the ICIQ-URV Master Programme; supervision of 3 Master Thesis.