Manuel Perucho completed his PhD in Biological Sciences at the University of Madrid, Spain, in 1976 and continued as a postdoctoral at the Max-Planck-Institut, Berlin. In 1979 he moved to Cold Spring Harbor Laboratory, and in 1983 to the State University of New York (SUNY) at Stony Brook, New York. In 1988 he moved to California Institute for Biological Research (CIBR) and in 1995 to Sanford-Burnham Medical Research Institute (SBMRI), both in La Jolla, California. He was appointed Director of the Institute of Predictive and Personalized Medicine of Cancer (IMPPC) of Barcelona in 2008. His work has pioneered landmarks in the molecular basis of cancer, including the discovery of the human oncogenes in the 80's and the mutator phenotype in the 90's. Among other prizes and awards, he was recipient of a Merit Award from the National Cancer Institute for NIH grant CA 63585 and the AACR-National Foundation for Cancer Research Professorship in Basic Cancer Research in 2003.