Antonio Postigo

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)

Life & Medical Sciences

* ICREA Research Professor. IDIBAPS (Barcelona).
* Adjunct Visiting Professor, JG Brown Cancer Center (USA)

*  Research Instructor & Special Fellow (Div Mol. Oncology, Washington Univ, USA)
* Research Associate and Fellow (Depts. of Cell Biology & Medicine, Washington Univ, USA)
* PhD student (Dept. of Immunology, Hosp. de la Princesa, Madrid)

* Public agencies: Spanish Ministry of Economy & Competitiveness, AGAUR, European Commission
* Private institutions: Leukemia Research Foundation, La Marató de TV3 Foundation, Spanish Association Against Cancer, AVON Breast Cancer Campaign, La Caixa Foundation, Olga Torres Foundation, Academy of Medical and Health Sciences of Catalonia & Balearic Islands

Research interests

The group investigates the molecular mechanisms regulating gene expression during cell differentiation and cancer. As molecular model we use the ZEB family of transcription factors (ZEB1 and ZEB2) and their different cofactors. Research in the laboratory aims at understanding the expression and function of ZEB factors in stem cell determination, normal cell differentiation, malignant transformation and tumor initiation and progression. Our work involves cell line and human tissue based approaches as well as in vivo mouse models in normal and malignant cells from multiple tissue systems, namely, epithelial, skeletal muscle and hematopoietic.

Selected research activities

Grant evaluator during 2016: Medical Research Council (UK), Cancer Research UK (UK) and Czech Science Foundation (Czech Republic).