Giuseppe Battaglia

Giuseppe Battaglia

Institut de Bioenginyeria de Catalunya

Engineering Sciences

Giuseppe, or as most people call him, Beppe, holds a Laurea in Chemical Engineering from the University of Palermo and PhD in Physical Chemistry from the University of Sheffield. Beppe joined the Catalan Institution for Research and Advanced Studies (ICREA) and the Institute of Bioengineering of Catalunya (IBEC) in 2019 and he's currently affiliated with the University College London in UK where he holds EPSRC Established Career fellowship unitl 2022 and, the Chair in Molecular Bionics in the Department of Chemistry. Priot to UCL Beppe held positions as Lecturer -2006, Senior Lecturer -2009 and Professor -2011 in the Departments of Materials Sci. Eng. (2006-2009) and Biomedical Science (2009-2013) at the University of Sheffield.   

Research interests

I have put together a truly interdisciplinary collection of research activities where we address biological challenges (often associated with a specific clinical need) using a constructionist approach. I have christened this approach Molecular Bionics and I mimic biological complexity in the form of design principles to produce functional units from simple building blocks and their interactions. We employ Chemistry and Physics together to engineer synthesis and characterisation of novel hierarchal materials whose properties are the result of the holistic combination of its components (Molecular Engineering). We apply these for tackling clinical challenges associated with drug delivery and diagnostics where we engange with clinicians to design new therapies (Nanomedicine). We study in detail transport phenomena in our body to shed light on how material is tranported and processed as well as biological barrer can be overcame (Physical Biology).

Selected publications

- Liu, Meng; Apriceno, Azzurra; Sipin, Miguel; Scarpa, Edoardo; Rodriguez-Arco, Laura; Poma, Alessandro; Marchello, Gabriele; Battaglia, Giuseppe; Angioletti-Uberti, Stefano 2020, 'Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions', Nature Communications, 11, 1, 4836.

- Tian, Xiaohe; Leite, Diana Moreira; Scarpa, Edoardo; Nyberg, Sophie; Fullstone, Gavin; Forth, Joe; Matias, Diana Lourenco; Apriceno, Azzurra; Poma, Alessandro; Duro-Castano, Aroa; Vuyyuru, Manish; Harker-Kirschneck, Lena; Saric, Andela; Zhang, Zhongping; Xiang, Pan; Fang, Bin; Tian, Yupeng; Luo, Lei; Rizzello, Loris; Battaglia, Giuseppe 2020, 'On the shuttling across the blood-brain barrier via tubule formation: Mechanism and cargo avidity bias', Science Advances, 6, 48, eabc4397.

- Tian X, Angioletti-Uberti S & Battaglia G* 2020, ''On the design of precision nanomedicines. Science Adv.  Vol. 6, no. 4, eaat0919.

- Fenaroli, Federico; Robertson, James D; Scarpa, Edoardo; Gouveia, Virginia M; Di Guglielmo, Claudia; De Pace, Cesare; Elks, Philip M; Poma, Alessandro; Evangelopoulos, Dimitrios; Canseco, Julio Ortiz; Prajsnar, Tomasz K; Marriott, Helen M; Dockrell, David H; Foster, Simon J; McHugh, Timothy D; Renshaw, Stephen A; Marti, Josep Samitier; Battaglia, Giuseppe; Rizzello, Loris 2020, 'Polymersomes Eradicating Intracellular Bacteria.', Acs Nano, 14, 7, 8287 - 8298.

- Tian, Xiaohe; De Pace, Cesare; Ruiz-Perez, Lorena; Chen, Bo; Su, Rina; Zhang, Mingzhu; Zhang, Ruilong; Zhang, Qiong; Wang, Qin; Zhou, Hongping; Wu, Jieying; Zhang, Zhongping; Tian, Yupeng; Battaglia, Giuseppe 2020, 'A Cyclometalated Iridium (III) Complex as a Microtubule Probe for Correlative Super-Resolution Fluorescence and Electron Microscopy', Advanced Materials, , 2003901.