Giuseppe Battaglia

Giuseppe Battaglia

Institut de Bioenginyeria de Catalunya

Engineering Sciences

Giuseppe (Beppe) has been an ICREA Professor at the Institute for Bioengineering of Catalonia (IBEC) since 2019, where he founded and leads the Molecular Bionics Group, which blends chemistry, physics, and engineering to advance nanomedicine. He is also a visiting professor at UCL and Sichuan University. As the founder of Vianautis Bio Ltd, he aims to develop genetic nanomedicines. Previously, he held a personal chair at UCL from 2013 to 2022 and in Sheffield from 2011 to 2013. His accolades include the Human Frontier Science Award, five ERC Grants, EPSRC Fellowships, the McBain Medal, and multiple fellowships with the Royal Societies of Chemistry and Biology. He has received the GSK Emerging Scientist Award, the Jingswa Friendship Award, and the Anhui 100 Talent Award. According to Stanford University, he has made significant contributions to materials science, polymer physics, and bioengineering and is now among the world’s top 2% of scientists, according to Stanford University.

Research interests

At the Molecular Bionics Group, we explore molecular and cellular trafficking across biological barriers, merging microscopy, theoretical physics, and computation to decode transport at molecular, membrane, and vasculature levels. Our insights into receptor clustering, protein aggregation, and membrane trafficking shed light on neurodegeneration, cancer, and immune disorders. We mimic these biological processes using synthetic analogues to influence them therapeutically. Leveraging molecular engineering, we design supramolecular drugs—smart therapeutics with enhanced precision, capable of modulating biological pathways like receptor clustering and pro-drug activation. These cutting-edge therapies are being tested for dementia, cancer, and immune disorders. Our mission is to seamlessly integrate medicine with biology, physics, and chemistry, redefining the future of healthcare.

Selected publications

- Chen JY, Xiang P, Duro-Castano A, Cai HW, Guo B, Liu XQ, Yu YF, Lui S, Luo K, Ke BW, Ruiz-Pérez L, Gong QY, Tian XH & Battaglia G 2025, 'Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood-brain barrier transport', Signal transduction and targeted therapy, 10 - 1 - 331.
- Ju, XH et al. 2025, 'Technology Roadmap of Micro/Nanorobots', Acs nano, 19 - 27 - 24174 - 24334.
- Ding HT, Su LP, Xie ZD, Castano AD, Li YK, Perez LR, Chen JY, Luo K, Tian XH & Battaglia G 2025, 'Morphological insights in oxidative sensitive nanocarrier pharmacokinetics, targeting, and photodynamic therapy', Journal of materials chemistry b, 13 - 12.
- Venugopal A, Ghosh S, Calò A, Tuveri GM, Battaglia G & Kumar M 2025, 'Enzyme Controlled Transient Phospholipid Vesicles for Regulated Cargo Release', Angewandte chemie-international edition.
- Barbieri V, Colsa JG, Matias D, Castano AD, Thapa A, Ruiz-Pérez L, Albella P, Volpe G & Battaglia G 2025, 'Thermoplasmonic Polymersome Membranes by In Situ Synthesis', Acs nano, 19 - 16 - 15331 - 15344.
- Borges-Fernandes B, Apriceno A, Arango-Restrepo A, Almadhi S, Ghosh S, Forth J, López-Alonso JP, Ubarretxena-Belandia I, Rubi JM, Ruiz-Pérez L, Williams I & Battaglia G 2025, 'The minimal chemotactic cell', Sci Adv. 11 - 30 -eadx9364.