Gustavo Deco

Gustavo Deco

Universitat Pompeu Fabra

Engineering Sciences

Gustavo Deco is Research Professor at ICREA and Professor (Catedrático) at the Pompeu Fabra University where he leads the Computational Neuroscience group. He is Director of the Center of Brain and Cognition (UPF). In 1987 he received his PhD in Physics for his thesis on Relativistic Atomic Collisions. In 1987, he was a postdoc at the University of Bordeaux in France. From 1988 to 1990, he was postdoc of the Alexander von Humboldt Foundation at the University of Giessen in Germany. From 1990 to 2003, he lead the Computational Neuroscience Group at Siemens Corporate Research Center in Munich, Germany. He obtained in 1997 his Habilitation (maximal academical degree in Germany) in Computer Science (Dr. rer. nat. habil.) at the Technical University of Munich for his thesis on Neural Learning. In 2001, he received his PhD in Psychology at the Ludwig-Maximilians-University of Munich. He was awarded an ERC Advanced Grant and recently with a second ERC Synergy

Research interests

Perceptions, memories, emotions, and everything that makes us human, demand the flexible integration of information represented and computed in a distributed manner. Normal brain functions require the integration of functionally specialized but widely distributed brain areas. The main aim of my research is to elucidate precisely the computational principles underlying higher brain functions and their breakdown in brain diseases. My research allows us to comprehend the mechanisms underlying brain functions by complementing structural and activation based analyses with dynamics. We integrate different levels of experimental investigation in cognitive neuroscience (from the operation of single neurons and neuroanatomy, neurophysiology, neuroimaging and neuropsychology to behaviour) via a unifying theoretical framework that captures the neural dynamics inherent in the computation of cognitive processes.

Selected publications

- Escrichs A, Perl YS, Fisher PM, Martínez-Molina N, Guzman EG, Frokjaer VG, Kringelbach ML, Knudsen GM & Deco G 2025, 'Whole-brain turbulent dynamics predict responsiveness to pharmacological treatment in major depressive disorder', Mol Psychiatry, 30-1069-1079.
- Vohryzek J, Sanz-Perl Y, Kringelbach ML & Deco G 2025, 'Human brain dynamics are shaped by rare long- range connections over and above cortical geometry', Proceedings of the national academy of sciences of the united states of america, 122 - 1 - e2415102122.
- Deco G, Perl YS & Kringelbach ML 2025, 'Complex harmonics reveal low-dimensional manifolds of critical brain dynamics', Physical review e, 111 - 1 - 014410.
- Deco G, Perl YS, Jerotic K, Escrichs A & Kringelbach ML 2025, 'Turbulence as a framework for brain dynamics in health and disease', Neuroscience and biobehavioral reviews, 169 -105988.
- Geli SM, Lynn CW, Kringelbach ML, Deco G & Perl YS 2025, 'Non-equilibrium whole-brain dynamics arise from pairwise interactions', Cell reports physical science, 6 - 3 -102464.
- Mana L, López-González A, Alemán-Gómez Y, Baumann PS, Jenni R, Alameda L, Empson LA, Klauser P, Conus P, Hagmann P, Vila-Vidal M & Deco G 2025, 'Subgroup-specific brain connectivity alterations in early stages of psychosis', Nature mental health, 3 - 4.
- Perl YS, Geli S, Perez-Ordoyo E, Zonca L, Idesis S, Vohryzek J, Jirsa VK, Kringelbach ML, Tagliazucchi E & Deco G 2025, 'Modelling low-dimensional interacting brain networks reveals organising principle in human cognition', Network neuroscience, 9 - 2 - 661 - 681.
- Deco G, Perl YS & Kringelbach ML 2025, 'Non-local Schrodinger diffusion model reveals mechanisms of critical brain dynamics', Cell reports physical science, 6 - 7 - 102663.
- Acero-Pousa I, Escrichs A, Dagnino PC, Perl YS, Kringelbach ML, Uhlhass PJ & Deco G 2025, 'Reconfiguration of functional brain hierarchy in schizophrenia', Translational psychiatry, 15 - 1 - 356.

Selected research activities

Publications of 36 high impact papers in 2025.