Turgut Durduran

Turgut Durduran

Institut de Ciències Fotòniques

Engineering Sciences

November 2015 – ICREA Research Professor; February 2009 - Group Leader – Medical Optics. Dr. Turgut Durduran is a group leader at ICFO. He moved to ICFO from University of Pennsylvania (USA) to found the ICFO-Medical Optics group in 2009, received tenure in 2014 and became an ICREA processor in 2015. Over the years, the group has grown exponentially, currently, with a large number of PhD students, post-docs and engineers collaborating with many hospitals and biomedical institutes world-wide. He has coordinated projects funded by the European Commission, Spanish National Ministries and the National Institutes of Health. He is active in bench-to-bedside translation of diffuse optical technologies including spin-off generation and medical device approvals.

Research interests

My work focuses on medical applications of diffuse light through the use of the phys
ical models of photon propagation in tissues, including the speckle statistics of diffuse light. In a
nutshell, I take advantage of the fact that light could travel many centimeters in living tissues and
carry clinically and physiologically relevant information from “deep” (>1 cm) tissue volumes. This
enables us to combine advanced physical models, instrumentation and algorithms to explore clinical
and basic biomedical applications.
We mostly focus on quantifying local, microvascular blood oxygenation, blood volume and blood
flow that are three quantities critical to sustaining cellular oyxgen metabolism. Their quantification
and the derivation of additional parameters from combination with other physiological parameters
and also through their dynamic patterns is very relevant in understanding development, normal tis
sue tissues and their impairments.

Selected publications

- Tagliabue S, Lindner C, Chochron da Prat I, Sanchez-Guerrero A, Serra I, Kacprzak M, Maruccia F, Martinez Silva O, Weigel UM, de Nadal M, Poca MA & Durduran T 2023, 'Comparison of cerebral metabolic rate of oxygen, blood flow, and bispectral index under general anesthesia', Neurophotonics, 10(1), 015006.

- Gregori-Pla C, Zirak P, Cotta G, et al. 2023, 'How does obstructive sleep apnea alter cerebral hemodynamics?', Sleep, 46, 8.
- Tagliabue S, Kacprzak M, Serra I, Maruccia F, Fischer JB, Riveiro M, Rey-Perez A, Exposito L, Lindner C, Báguena M, Durduran T & Poca MA, 2023 'Transcranial, noninvasive evaluation of the potential misery perfusion during hyperventilation therapy of traumatic brain injury patients', Journal of Neurotrauma, 40, 19-20.
- Parfentyeva V, Colombo L, Lanka P, Pagliazzi M, Brodu A, Noordzij N, Kolarczik M, Dalla MA, Re R, Contini D, Torricelli A, Durduran T & Pifferi A 2023, 'Fast time-domain diffuse correlation spectroscopy with superconducting nanowire single-photon detector: system validation and in vivo results', Sci Rep 13, 11982.
- Harvey-Jones K, Lange F, Verma V, Bale G, Meehan C, Avdic-Belltheus A, Hristova M, Sokolska M, Torrealdea F, Golay X, Parfentyeva V, Durduran T, et al. 2023, 'Early assessment of injury with optical markers in a piglet model of neonatal encephalopathy', Pediatric Research

- Lin CHP, Orukari I, Tracy C, Kobayashi Frisk L, Verma M, Chetia S, Durduran T, Trobaugh JW & Culver JP 2023, 'Multi-mode fiber-based speckle contrast optical spectroscopy: analysis of speckle statistics', Opt Lett, 48, 1427-1430.