Dr. Marquès-Bonet is the Principal Investigator of the group "Comparative Genomics" and director of the Institute of Evolutionary Biology (IBE; UPF/CSIC) and at the CRG-CNAG. He started his own lab in 2010 with an ERC Starting Grant and was selected as ICREA in 2011. In 2013 he was selected for the EMBO young Investigator award. Starting on 2017 he is an HHMI International young investigator. His group aims to characterize human specific genomics features, including the combination of evolution and conservation genetics. With a total of more than 200 peer-reviewed publications, he has published as a senior authorship in Science (2023(x3), 2016,2020), Nature (2013;2019, 2024), Genome Research (2015,2021), Plos Genetics (2013,2015) among others. He was director of the Institute of Evolutionary Biology (UPF-CSIC), 2017-2020. He was awarded with an ERC Consolidator 2019. He published a Special Issue in Science (5 articles) in 2023 dedicated to Primate Genomics.
Research interests
What makes us human? This is a fundamental question in many disciplines. Our team analyzes a wide range of genome variants to determine processes, variants and molecular features that are intrinsic to our species. To do so, we study full genome, epigenomes and transcriptomic sequences of humans and great apes for a better understanding of human specific features.
Selected publications
- Kuderna LFK, Gao H, Janiak MC, et al. 2023, 'A global catalog of whole-genome diversity from 233 primate species', Science, 380, 6648, 906 - 912.
- Sørensen EF, Harris RA, Zhang L, et al. 2023, 'Genome-wide coancestry reveals details of ancient and recent male-driven reticulation in baboons', Science, 380, 6648, eabn8153.
- Gao H, Hamp T, Ede J, et al. 2023, 'The landscape of tolerated genetic variation in humans and primates', Science, 380, 6648, eabn8197.
- Murat F, Mbengue N, Winge SB et al. 2023, 'The molecular evolution of spermatogenesis across mammals', Nature, 613, 308–316.