Andreas Meyerhans

Andreas Meyerhans

Universitat Pompeu Fabra

Life & Medical Sciences

University Education - 1987 PhD in Chemistry, University of Hamburg, Germany. - 1982 Diploma in Chemistry, University of Hamburg, Germany. Professional Positions - Since 2010 ICREA Research Professor at Pompeu Fabra University, Barcelona. - 1998-2009 Full Professor, Saarland University, Germany. - 1990-1998 Assistant Professor, University of Freiburg, Germany. - 1988-1990 Postdoctoral Fellow, Institute Pasteur, Paris, France. - 1987-1988 Postdoctoral Fellow, Institute Biotechnological Research, Braunschweig, Germany.

Research interests

Infections with non-cytopathic viruses usually have 2 different outcomes. They may be eliminated by host immune responses (acute infections) or they may persist lifelong (persistent infections). Medically important examples are the Hepatitis B virus (HBV), the Human Immunodeficiency virus (HIV) and the Hepatitis C virus (HCV) that in adults usually follow an acute (HBV), a persistent (HIV) or an either acute or persistent (HCV) infection course. My laboratory is interested (i) to understand the factors that regulate the decision between an acute versus a persistent infection course, (ii) to define the factors that control the dynamic balance of virus expansion and immune control in persistent infections, (iii) to design immunogens to inhibit virus infections, and (iv) to generate quantitative descriptions of the virus/immune system dynamics by mathematical modeling.

Selected publications

- Sazonov I, Grebennikov D, Meyerhans A & Bocharov G, 2022, 'Sensitivity of SARS-CoV-2 Life Cycle to IFN Effects and ACE2 Binding Unveiled with a Stochastic Model', Viruses-basel, 14, 2, 403.

- Sistere-Oro M, Wortmann D D J, Andrade N, Aguilar A, Mayo de las Casas C, Garcia Casabal F, Torres S, Bonas Salinas E, Raventos Soler L, Arcas A, Esparre C, Garcia B, Valarezo J, Rosell R, Guerri-Fernandez R, Gonzalez-Cao M & Meyerhans A 2022, 'Brief Research Report: Anti-SARS-CoV-2 Immunity in Long Lasting Responders to Cancer Immunotherapy Through mRNA-Based COVID-19 Vaccination', Frontiers In Immunology, 13, 908108.

- Bocharov G, Grebennikov D, Cebollada Rica P, Domenjo-Vila E, Casella V & Meyerhans A 2022, 'Functional cure of a chronic virus infection by shifting the virus-host equilibrium state', Frontiers In Immunology, 13, 904342.

- Grebennikov D, Karsonova A, Loginova M, Casella V, Meyerhans A & Bocharov G. 2022, ´Predicting the kinetic coordination of immune response dynamics in SARS-CoV-2 infection: implications for disease pathogenesis´, Mathematics, 10(17), 3154. 

- Sisteré-Oró M, Andrade N, Wortmann DDJ, Du J, Garcia-Giralt N, González-Cao M, Güerri-Fernández R & Meyerhans A 2022, ´Anti-SARS-COV-2 specific immunity in HIV immunological non-responders after mRNA-based COVID-19 vaccination´ Front Immunol. 13:994173.

Selected research activities

Co-organizer of the International Conference “Mathematics Applied to Immunology and Virology” held at the Sirius Mathematics Centre, Sochi (Russia), June 6-10, 2022
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