Arcadi Navarro

Arcadi Navarro

Universitat Pompeu Fabra

Life & Medical Sciences

Arcadi got a PhD in Biology at the UAB. After quitting academia for a few years, he went back to research as a postdoc at the University of Edinburgh. He entered the UPF in 2002 and joined ICREA in 2006. Between 2008-13 he was vice-director of the Institute for Evolutionary Biology (IBE), a joint UPF-CSIC initiative. Since 2010 he is Professor of Genetics at the UPF and leads a group on Evolutionary Genomics within the Department of Experimental and Health Sciences. He directed that Department between 2013 and 2016, a time during which he started a collaboration with the CRG, the EMBL-EBI and the BSC to co-direct the European Genome-Phenome Archive. In 2016 he left academy again to become Secretary for Universities and Research at the Generalitat de Catalunya. He left government in 2018 and, after a short sabbatical, he returned to all his previous appointments in January 2019. He is happy to be back!!!

Research interests

Life as we see it in our planet today has been shaped by many different biological processes during billions of years. These processes leave complex and fascinating signatures in our genomes in the form of differences between species, or between individuals of the same species. By interrogating these patterns of genome diversity we can infer what are the forces that affect living organisms, how and when they act and how do they affect such various things as biodiversity, ageing or the differential susceptibility of different persons to certain diseases. All this knowledge empowers us to control our future but, above all, it is fun to obtain.

Selected publications

– Maria Heredia-Genestar, Jose; Marques-Bonet, Tomas; Juan, David; Navarro, Arcadi 2020, ‘Extreme differences between human germline and tumor mutation densities are driven by ancestral human-specific deviations’, Nature Communications, 11, 1, 2512.

– Farré X, Spataro N, Haziza F, Rambla J & Navarro A 2020, ‘Genome-phenome explorer (GePhEx): a tool for the visualization and interpretation of phenotypic relationships supported by genetic evidence’, Bioinformatics, 36, 3, 890 – 896.

– Santpere, Gabriel; Telford, Marco; Andres-Benito, Pol; Navarro, Arcadi; Ferrer, Isidre 2020, ‘The Presence of Human Herpesvirus 6 in the Brain in Health and Disease’, Biomolecules, 10, 11, 1520.

– The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium (including Navarro A) 2020, ‘Pan-cancer analysis of whole genomes’. Nature 578: 82–93.

– Brasó-Vives, M., I. S. Povolotskaya, D. A Hartasánchez, X. Farré, M. Fernandez-Callejo, M. Raveendran, R. A. lan Harris, D. L. Rosene, B. Lorente-Galdos, A. Navarro, T. Marques-Bonet, J. Rogers, D. Juan. 2020, ‘Copy number variants and fixed duplications among 198 rhesus macaques (Macaca mulatta)‘. PLoS Genetics 16: e1008742 .

– Telford, Marco; Hughes, David A.; Juan, David; Stoneking, Mark; Navarro, Arcadi; Santpere, Gabriel 2020, ‘Expanding the Geographic Characterisation of Epstein-Barr Virus Variation through Gene-Based Approaches’, Microorganisms, 8, 11, 1686.

– Gelabert P et al. 2020, ‘Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet’, Current Biology, 30, 1, 108 – +.