Ciara O' Sullivan received a BSc in Analytical Chemistry from Dublin City University in 1992, a PhD in Biotechnology from Cranfield University in 1996 and then went on to lead the sensors group at University College Cork from 1996-99. She then took up a Marie Curie Fellowship at the Universitat Rovira i Virgili (1999-2001) and was then awarded a Ramón y Cajal Fellowship which she pursued for 1 year prior to taking up her current position as ICREA Research Professor and establishing the Nanobiotechnology and Bioanalysis Group at the Universitat Rovira i Virgili. She is group leader of the GENCAT funded Consolidated Group INTERFIBIO. Her group details can be found at www.interfibio.com.
Research interests
Her research interests lie in the development of electrochemical and optical biosensors exploiting advances in tailored biocomponents. Presently, her work focuses on reducing to practise cost-effective molecular diagnostics for screening and monitoring of disease, as well as on the development of aptamers for application in optical and electrochemical molecular aptamer beacons. The approaches for molecular diagnostics being developed include parallelised real-time electrochemical next generation sequencing, electrochemical array based primer extension and elongation for multiplexed SNP detection, multiplexed electrochemical miRNA detection and quantitative paper diagnostics as companion tools for the future paradigm of pharmacogenomics and personalised medicine.
Selected publications
- Yenice CP, Chahin N, Jauset-Rubio M, et al. 2023, 'Semiautomated Electrochemical Melting Curve Analysis Device for the Detection of an Osteoporosis Associated Single Nucleotide Polymorphism in Blood', Analytical Chemistry, 95, 38, 14192-14202.
- Ortiz M, Jauset-Rubio M, Trummer O, et al. 2023, 'Generic Platform for the Multiplexed Targeted Electrochemical Detection of Osteoporosis-Associated Single Nucleotide Polymorphisms Using Recombinase Polymerase Solid-Phase Primer Elongation and Ferrocene-Modified Nucleoside Triphosphates', Acs Central Science, 9, 8, 1591-1602.
- Kodr D, Ortiz M, Sykorova V, et al. 2023, 'Normalized Multipotential Redox Coding of DNA Bases for Determination of Total Nucleotide Composition', Analytical Chemistry, 95, 34, 12586-12589.
- Molejon NA, Lapada CM, Skouridou V, et al.. 2023, 'Selection of G-rich ssDNA aptamers for the detection of enterotoxins of the cholera toxin family', Analytical Biochemistry, 669, 115118.
- Torregrosa D, Jauset-Rubio M, Serrano R, et al. 2023, 'Ultrasensitive determination of ?-conglutin food allergen by means an aptamer assay based on inductively coupled plasma mass spectrometry detection', Analytica Chimica Acta, 1252, 341042.