Antonio Postigo

Antonio Postigo

Institut d'Investigacions Biomèdiques August Pi i Sunyer

Life & Medical Sciences

CURRENT POSITIONS:  * ICREA Professor of Life & Medical Sciences. IDIBAPS Research Institute (Barcelona) * Adjunct Visiting Professor, JG Brown Cancer Center, Univ. Louisville School of Medicine (USA) * Adjunct Lecturer, Dept. of Biomedicine. Univ. of Barcelona School of Medicine (Barcelona)


* Public Agencies: European Commission / Spanish Ministry of Science & Innovation / Catalan Agency for University & Research Grants (AGAUR)

* Private Foundations: Leukemia Research Foundation / Duchenne Parent Project / AVON Breast Cancer Campaign / Spanish Association Against Cancer (AECC) / La Marató TV3 Foundation / Olga Torres Foundation / La Caixa Foundation / Catalan Academy of Medical & Health Sciences.


Research interests

Our group studies the molecular mechanisms that regulate cell plasticity in health and disease with a particular focus on transcriptional regulation. Ongoing projects investigate gene regulation in inflammation, cancer initiation and progression, stem cell determination and differentiation, and tissue injury and regeneration. We use a wide range of technical approaches that include unique conditional transgenic mice, ex vivo culture and manipulation of normal and malignant primary cells, differentiation of human embryonic stem cells, and high-throughput techniques (e.g., RNAseq, proteomics). As molecular models, we use the EMT transcription factors ZEB1 and ZEB2 which play key roles in the regulation of cell plasticity.

Selected research activities

Director of PhD dissertations that were defended during 2020

Núria Profitós Pelejà (Univ of Barcelona), PhD awarded in July 2020