Ángel Raya is an ICREA Research Professor at the Bellvitge Biomedical Research Institute (IDIBELL). He obtained his MD in 1990 from the University of Valencia, Spain and a PhD degree from the same university in 1995 for studies carried out at the Department of Physiology and at the Department of Neurology, Mayo Clinic, Rochester, MN. He pursued postdoctoral training at the Instituto de Investigaciones Citológicas (currently, Centro de Investigación Príncipe Felipe) in Valencia, from 1995-2000. He then was a Research Associate (2000-2004) and a Senior Research Associate (2004-2006) in the Gene Expression Laboratory of the Salk Institute for Biological Studies, La Jolla, CA. He returned to Spain in 2006 and was the Scientific Coordinator at the CMRB until 2009, when he joined the Institute for Bioengineering of Catalonia (IBEC) as Group Leader of the Control of Stem Cell Potency group, until 2015. From 2014 to 2019 he was Director at CMRB.
Research interests
Our research work aims to understand the tissue, cellular and molecular mechanisms that determine the regenerative response in certain species of vertebrates, as well as the genetic and epigenetic mechanisms that control cellular reprogramming. This phenomenon provides a link between the traditional study of epimorphic regeneration and the induced pluripotency strategies of regenerative medicine.
Selected publications
- Pons-Espinal M, Blasco-Agell L, Fernandez-Carasa I, Andrés-Benito P, di Domenico A, Richaud-Patin Y, Baruffi V, Marruecos L, Espinosa L, Garrido A, Tolosa E, Edel MJ, Otero MJ, Mosquera JL, Ferrer I, Raya A & Consiglio A 2024, 'Blocking IL-6 signaling prevents astrocyteinduced neurodegeneration in an iPSCbased model of Parkinson's disease', Jci insight, 9 - 3.
- Medina LC, Pourchet L, Patin YR & Raya A 2024, 'Human 3D bioprinted tubular cardiac tissues as a tool for cardiac therapies', European journal of clinical investigation, 54.
- Litowczenko J, Richter Y, Michalska M, Tadevosyan K, Rodriguez-Cabello JC, Casado L, Papakonstantinou I & Raya A 2024, 'Development of tissue-engineered cell-laden vascular grafts with micro/nano topographical cues from human induced pluripotent stem cell derivatives', European journal of clinical investigation, 54.
Selected research activities
Invited speaker:
Scientific meeting on “An open window on stem cells” Università degli Studi di Brescia, January
7th Congress of the Hellenic Society of Gene Therapy and Regenerative Medicine, Thessaloniki, May
58th Annual Scientific Meering of the European Society for Clinical Investigation, Barcelona, June
2nd WCH-IBEC Precision Medicine Conference, Chengdu, September
Co-organizer
Symposium 5: Gene, Cell Therapy, and Oncology. 58th Annual Scientific Meering of the European Society for Clinical Investigation, Barcelona, June
2024 RegenBell Symposium on Stem Cells and Regenerative Medicine. Barcelona, November