Iñaki Ruiz  Trillo

Iñaki Ruiz Trillo

Institut de Biologia Evolutiva

Life & Medical Sciences

Iñaki Ruiz-Trillo is an ICREA Research Professor at the Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra). His educational background includes a B.S. and a Ph.D. in Biology from the University of Barcelona. Funded by grants from EMBO and the Canadian Institutes of Health Research, he completed a post-doctoral fellowship at Dalhousie University (Canada). He has also performed short term research projects at the Joint Genome Institute, the University of Arkansas and the Kavli Institute for Theoretical Physics. Iñaki has published more than 100 peer-reviewed articles, most of them in high impact journals, such as Cell, Nature, Science, eLife, PNAS. He has lead several research projects, including 3 ERC grants. He is an EMBO member and has served on the editorial board of several journals. He is currently head of the Complexity of Life program at the Insitute of Evolutionary Biology. His current research focus is on the origin of multicellular animals.

Research interests

The lab addresses one of the most important evolutionary transitions in the history of life: the origins of multicellularity. To this aim, we focus on the origin of multicellular animals. We perform comparative and functional genomic analyses between animals and their closest unicellular relatives. We reconstruct the nature of the unicellular ancestor that gave rise to animals. We have also developed the first "functional platform" to address animal origins, establishing several new model organisms specific to this question. Finally, we also unravel the hidden diversity of eukaryotes using metabarcoding data. 

Selected publications

- Shabardina V, Dharamshi JE Ara PS et al 2024, 'Ichthyosporea: a window into the origin of animals', Commun Biol 7, 915.
- Benvenuto, G et al. 2024, 'Evolution of the ribbon-like organization of the Golgi apparatus in animal cells', Cell reports, 43 - 3 - 113791.
- Richards TA, Eme L , Archibald JM , Leonard G, Coelho SM, de Mendoza A, Dessimoz C, Dolezal P, Fritz-Laylin LK, Gabaldón T, Hampl V, Geert J. P. L. Kops, Leger MM, Lopez-Garcia P, McInerney JO, Moreira D, Muñoz-Gómez SA, Richter DJ, Ruiz-Trillo I, Santoro AE, Sebé-Pedrós A, Snel B, Stairs CW, Tromer EE, van Hooff JJE, Wickstead B, Williams TA, Roger AJ , Dacks JB, Wideman JG 2024, "Reconstructing the last common ancestor of all eukaryotes" PLOS Biology 22 -11 - e3002917.