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Samuel Sánchez

Samuel Sánchez

Institut de Bioenginyeria de Catalunya

Engineering Sciences

Samuel (PhD Chemistry, UAB, 2008) is Group Leader at the Institute for Bioengineering of Catalonia (IBEC) and since 2019 Deputy Director. In 2009, he worked at NIMS, Japan, from 2010-2013 he was Group Leader at the Institute for Integrative Nanosciences, IFW Dresden, Germany. From 2013-2018 he was Group Leader at the Max Planck Institute for Intelligent Systems, Stuttgart. He was one of the first selected members of the Young Academy of Spain in 2020. He received several awards: Guinness World Record® 2010 and 2017 for smallest jet engine;  MIT TR35 as “Innovator of the year U35” Spain 2014; Princess of Girona Scientific Research Award 2015; and National Research Award for Young Talent from the FCRi, Catalonia, in 2016 among others. He has been awarded with ERC Starting Grant 2012, 2 ERC PoC 2016 and 2018 and the ERC-Consolidator Grant in 2019. He holds 7 patents, >150 publications, an h-index of 62 and >14000 cites.

Research interests

Samuel Sánchez is leader of the “Smart Nano-Bio-Devices” group, working in the multidisciplinary field of Nanosciences with interest in developing hybrid robotics systems across different length-scales, from the nano- to the macroscale. Research interest spans from fundamental science, translational approach of nanodevices to the clinic to the exploitation of the protected intellectual property developed by the group. Currently, the main research lines in the group are: 1. Nanofabrication of nanobots as smart drug delivery systems for biomedical applications such as bladder cancer treatment.; 2. Study of collective phenomena of active nanosystems; 3. Development of personalized medicine based on multifunctional biocompatible nanobots for patient-derived tumors and other diseases, 4. Use of medical imaging tools to track self-propelled nanobots in vivo and 4. 3D Printing living systems based on skeletal muscle tissues for tissue engineering, drug screening and living soft robotics.

Selected publications

– Hortelao AC, Simó C, Guix M, Guallar-Garrido S, Julián E, Vilela D, Rejc L, Ramos-Cabrer P, Cossío U, Gómez-Vallejo V, Patiño T, Llop J & Sánchez S 2021, ‘Swarming behavior and in vivo monitoring of enzymatic nanomotors within the bladder‘. Science Robotics, vol. 17, no. 6, pp eabd2823.

– Guix M, Mestre R, Patiño T, De Corato M, Fuentes J, Zarpellon G & Sánchez S. 2021, ‘Biohybrid soft robots with self-stimulating skeletons‘. Science Robotics, vol.6,no.53, pp eabe7577.

– Palacios, L. S., Tchoumakov, S., Guix, M., Pagonabarraga, I., Sánchez, S., & G Grushin, A. 2021. ‘Guided accumulation of active particles by topological design of a second-order skin effect‘, Nature commun.,vol. 2,no.1,pp 4691.

– Song, S., Mason, A. F., Post, R., De Corato, M., Mestre, R., Yewdall, N. A., Cao, S., van der Hofstad, R. W., Sanchez, S., Abdelmohsen, L., & van Hest, J. 2021, ‘Engineering transient dynamics of artificial cells by stochastic distribution of enzymes‘, Nature commun,vol.12, no.1,pp 1-9.

– Katuri J, Uspal WE, Popescu MN, Sánchez S. 2021, ‘Inferring non-equilibrium interactions from tracer response near confined active Janus particles‘, Science Advances, vol. 7, no. 18, pp eabd0719.

– Xu D, Hu J, Pan X, Sánchez S, Yan X, Ma X. 2021, ‘Enzyme-Powered Liquid Metal Nanobots Endowed with Multiple Biomedical Functions‘, Acs Nano,vol.15,no.7, pp 11543-11554.

– Vilela, D., Blanco-Cabra, N., Eguskiza, A., Hortelao, A. C., Torrents, E., & Sanchez, S. 2021. ‘Drug-Free Enzyme-Based Bactericidal Nanomotors against Pathogenic Bacteria‘. ACS appl.mater& Interf, vol.13, no.13,pp 14964–14973.

– Mestre, R., García, N., Patiño, T., Guix, M., Fuentes, J., Valerio-Santiago, M., Almiñana, N., & Sánchez, S. 2021, ‘3D-bioengineered model of human skeletal muscle tissue with phenotypic features of aging for drug testing purposes‘. Biofabrication, vol. 13, no, 4, pp 045011.

Selected research activities

>100 media apperances

-15 invited talks

-CaixaHealth Consortium as coordinator

-1 patent

-1PhD thesis

ICREA Memoir 2021